Books and Journal Covers of featured articles from our laboratory.
Books:
Lau Y-FC and Chan WY (2007). Editors, Y chromosome and Male Germ Cell Biology, World Scientific Press, New Jersey.
https://www.worldscientific.com/worldscibooks/10.1142/6303
Lau Y-F (1988). Editor, Endocrine Genes: Analytical Methods, Experimental Approaches and Selected Systems. Oxford University Press, New York
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1715493/
Featured articles in journals:
Kido T, Li YM, Tanaka Y, Dahiya R, Lau YC. The X-linked tumor suppressor TSPX downregulates cancer-drivers/oncogenes in prostate cancer in a C-terminal acidic domain dependent manner. Oncotarget, 2019, Feb 19, 10(15):1491-1505
https://www.ncbi.nlm.nih.gov/pubmed/30863497
Li Y, Zhang DJ, Qiu Y, Kido T, Lau YC. The Y-located proto-oncogene TSPY exacerbates and its X-homologue TSPX inhibits transactivation functions of androgen receptor and its constitutively active variants. Hum Mol Genet. 2017 03 01; 26(5):901-912.
https://academic.oup.com/hmg/article/26/5/901/2972794
Li Y, Kido T, Garcia-Barcelo MM, Tam PK, Tabatabai ZL, Lau YF. SRY interference of normal regulation of the RET gene suggests a potential role of the Y-chromosome gene in sexual dimorphism in Hirschsprung disease. Hum Mol Genet. 2015 Feb 1; 24(3):685-97.
https://academic.oup.com/hmg/article/24/3/685/2900943
Lau YF, Li Y, Kido T. Role of the Y-located putative gonadoblastoma gene in human spermatogenesis. Syst Biol Reprod Med. 2011 Feb; 57(1-2):27-34.
https://www.tandfonline.com/doi/full/10.3109/19396368.2010.499157
Kido T, Schubert S, Schmidtke J, Lau YFC. Expression of the human TSPY gene in the brains of transgenic mice suggests a potential role of this Y chromosome gene in neural functions. J Genet Genomics. 2011 May 20; 38(5):181-91.
https://www.sciencedirect.com/science/article/pii/S1673852711000592?via%3Dihub
Lau YF, Li Y, Kido T. Gonadoblastoma locus and the TSPY gene on the human Y chromosome. Birth Defects Res C Embryo Today. 2009 Mar; 87(1):114-22.
https://onlinelibrary.wiley.com/doi/abs/10.1002/bdrc.20144
Lau YF, Yang-Feng TL, Elder B, Fredga K, Wiberg UH. Unusual distribution of Zfy and Zfx sequences on the sex chromosomes of the wood lemming, a species exhibiting XY sex reversal. Cytogenet Cell Genet. 1992; 60(1):48-54.
https://www.ncbi.nlm.nih.gov/pubmed/?term=PMID%3A+1349859